Producción científica - Publicaciones más relevantes de los últimos años
PUBLICACIONES EN REVISTAS CIENTÍFICAS:
Fernández IF, Blanco S, Lozano J, Lazo PA.
VRK2 inhibits MAPK signaling and inversely correlates with ErbB2 in human breast cancer.
Mol Cell Biol. 30(19): 4687-97; 2010
Sánchez-Muñoz A, Gallego E, de Luque V, Pérez-Rivas LG, Vicioso L, Ribelles N, Lozano J, Alba E.
Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
BMC Cancer. 2010 Apr 13;10(1):136.
Jagemann LR, Pérez-Rivas LG, Ruiz EJ, Ranea JA, Sánchez-Jiménez
F, Nebreda AR, Alba E, Lozano J.
The functional interaction of 14-3-3 proteins with the ERK1/2 scaffold
KSR1 occurs in an isoform-specific manner.
J
Biol Chem. 283(25): 17450-17462; 2008
Lozano J, Xing R, Cai Z, Jensen HL, Trempus C, Mark W, Cannon R, Kolesnick
R.
Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling
in mice.
Cancer
Res 63(14): 4232-4238; 2003
Villanueva A, Lozano J, Morales A, Lin X, Deng X, Hengartner MO, Kolesnick
RN.
jkk-1 and mek-1 regulate body movement coordination and response to heavy
metals through jnk-1 in Caenorhabditis elegans.
EMBO
J. 20(18): 5114-5128; 2001
Lozano J, Morales A, Cremesti A, Fuks Z, Tilly JL, Schuchman E, Gulbins
E, Kolesnick R.
Niemann-Pick Disease versus acid sphingomyelinase deficiency.
Cell
Death Differ. 8(1): 100-103; 2001
Lozano J, Menendez S, Morales A, Ehleiter D, Liao WC, Wagman R, Haimovitz-Friedman
A, Fuks Z, Kolesnick R.
Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.
J
Biol Chem. 276(1): 442-448; 2001
Xing, H.R., J. Lozano, & R. Kolesnick.
Epidermal growth factor treatment enhances the kinase activity of kinase
suppressor of Ras.
J
Biol Chem. 275(23): 17276-17280; 2000
van der Houven van Oordt W, Diaz-Meco MT, Lozano J, Krainer AR, Moscat
J, Cáceres JF.
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution
of hnRNP A1 and modulates alternative splicing regulation.
J
Cell Biol. 149(2): 307-316; 2000
Basu S, Bayoumy S, Zhang Y, Lozano J, Kolesnick R.
BAD enables ceramide to signal apoptosis via Ras and Raf-1.
J
Biol Chem. 273(46): 30419-30426; 1998
García-Rocha M, Avila J, Lozano J.
The zeta isozyme of protein kinase C binds to tubulin through the pseudosubstrate
domain.
Exp
Cell Res. 230(1): 1-8; 1997
Diaz-Meco MT, Municio MM, Sanchez P, Lozano J, Moscat J.
Lambda-interacting protein, a novel protein that specifically interacts
with the zinc finger domain of the atypical protein kinase C isotype
lambda/iota and stimulates its kinase activity in vitro and in vivo.
Mol
Cell Biol. 16(1): 105-114; 1996
Díaz-Meco MT, Municio MM, Frutos S, Sanchez P, Lozano J, Sanz
L, Moscat J.
The product of par-4, a gene induced during apoptosis, interacts selectively
with the atypical isoforms of protein kinase C
Cell
86(5): 777-786; 1996
Municio MM, Lozano J, Sánchez P, Moscat J, Diaz-Meco MT.
Identification of heterogeneous ribonucleoprotein A1 as a novel substrate
for protein kinase C zeta.
J
Biol Chem. 270(26): 15884-15891; 1995
Medina MA, García de Veas R, Morata P, Lozano J, Sánchez-Jiménez
F.
Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and
the proliferation of human breast cancer cell lines.
Breast
Cancer Res Treat. 35(2): 187-194; 1995
Berra E, Díaz-Meco MT, Lozano J, Frutos S, Municio MM, Sánchez
P, Sanz L, Moscat J.
Evidence for a role of MEK and MAPK during signal transduction by protein
kinase C zeta.
EMBO
J. 14(24): 6157-6163; 1995
Sanz L, Berra E, Municio MM, Dominguez I, Lozano J, Johansen T, Moscat
J, Diaz-Meco MT.
Zeta PKC plays a critical role during stromelysin promoter activation
by platelet-derived growth factor through a novel palindromic element.
J
Biol Chem. 269(13): 10044-1049; 1994
Lozano J, Berra E, Municio MM, Diaz-Meco MT, Dominguez I, Sanz L, Moscat
J.
Protein kinase C zeta isoform is critical for kappa B-dependent promoter
activation by sphingomyelinase.
J
Biol Chem. 269(30): 19200-19202; 1994
Gil-Torregrosa B, Urdiales JL, Lozano J, Mates JM, Sanchez-Jimenez F.
Expression of different mitogen-regulated protein/proliferin mRNAs in
Ehrlich carcinoma cells.
FEBS
Lett. 349(3): 343-348; 1994
Diaz-Meco MT, Dominguez I, Sanz L, Dent P, Lozano J, Municio MM, Berra
E, Hay RT, Sturgill TW, Moscat J.
zeta PKC induces phosphorylation and inactivation of I kappa B-alpha
in vitro.
EMBO
J. 13(12): 2842-8; 1994
Diaz-Meco MT, Lozano J, Municio MM, Berra E, Frutos S, Sanz L, Moscat
J.
Evidence for the in vitro and in vivo interaction of Ras with protein
kinase C zeta.
J
Biol Chem. 269(50): 31706-31710; 1994
Diaz-Meco MT, Berra E, Municio MM, Sanz L, Lozano J, Dominguez I, Diaz-Golpe
V, Lain de Lera MT, Alcamí J, Payá CV
A dominant negative protein kinase C zeta subspecies blocks NF-kappa
B activation.
Mol
Cell Biol. 13(8): 4770-4775; 1993
Berra E, Diaz-Meco MT, Dominguez I, Municio MM, Sanz L, Lozano J, Chapkin
RS, Moscat J.
Protein kinase C zeta isoform is critical for mitogenic signal transduction.
Cell
74(3): 555-563; 1993
LIBROS Y CAPITULOS DE LIBRO:
Luís G. Pérez-Rivas, Stephanie Prieto and José Lozano
Modulation of Ras signaling by the KSR family of molecular scaffolds
Emerging Signaling Pathways in Tumor Biology (Ed. P.A. Lazo)
Transworld Research Network. Kerala, India (2010)
ISBN: 978-81-7895-477-6
José Lozano y Emilio Alba
Mecanismos de invasión, metástasis y angiogénesis
(Capítulo 5, pp 85-103)
Tratado de Oncología (Tomo I)
Editores: Hernán Cortés-Funés & Ramón
Colomer
Publicaciones Permanyer. Barcelona, España (2009)
ISBN: 978-84-92620-17-3
José Lozano
¿Cómo se desarrolla un cáncer?: la célula
fuera de control
Encuentros con la ciencia. del macrocosmos al microcosmos
E. Gutiérrez Marí Ed. Granada, España (2007)
ISBN: 13: 978-84-612-0114-3
Brent. D. Polk, José Lozano and Richard Kolesnick
Kinase Suppressor of Ras as a Ceramide-activated Protein Kinase (Chapter
7, pp.63-73)
Ceramide Signaling (Editor, A.H. Futerman)
Landes Biosciences Publisher. Texas, USA (2002)
ISBN: 0-306-47442-5
José Lozano and Richard Kolesnick
CAP (ceramide-activated protein) kinase (pp 727-729)
Wiley Encyclopedia of Molecular Medicine
John Wiley & Sons, Inc. New York, USA (2001)
ISBN: 978-0-471-37494-7
Diseñado por Proyecta Científica
